Retatrutide — GLP-1/GIP/Glucagon Triple Receptor Agonist
Retatrutide simultaneously activates three metabolic receptors: GLP-1R, GIPR, and the glucagon receptor. That triple mechanism sets it apart from dual agonists like tirzepatide and has placed it at the center of active Phase 2 and Phase 3 clinical investigation into metabolic signaling pathways.
Researchers use it to study:
- Triple receptor agonism and downstream hormonal signaling
- GLP-1, GIP, and glucagon receptor interactions
- Metabolic regulation at the multi-receptor level
- Comparative mechanisms vs. dual agonists (tirzepatide, semaglutide)
Lot LFG-RT-501 | Purity: 99.921% | Tested by Freedom Diagnostics | HPLC + Mass Spec verified
For research use only. Not for human or veterinary consumption. These statements have not been evaluated by the FDA.





